Radiology - Conditions (Subscribe)  

# polyostotic fibrous dysplasia
# precocious puberty (33% of females, rarely in males)
# cafe-au-lait spots (coast of Maine)

rare condition of cortical thickening of unknown etiology most commonly seen in the long bones
* 3-59 years
* sx: usu. pain of varying severity, occ. limited ROM, contracture
* insidious onset and chronic course
xray findings:
* cortical sclerosis and thickening that may encroach on the medullary canal -- looks like wax flowing down...

Radiology case 338-1452 Clinical presentation: Young adult female with a large head and in a wheel chair.
There are symmetrical defects in the ilia. The lumbar canal is widened at its lower end with the increased interpedicular distance just visible in this view. A wide defect visible in the bone density of...

defective intestinal copper absorption
* X-linked recessive
* males only
* presents in early infancy
* Wormian bones

a/k/a: craniometaphyseal dysplasia
* autosomal recessive
* failure of modeling of cylindrical bones
* "Erlenmeyer flask" appearance of metaepiphyses

Radiology case 471-3310 Clinical presentation: 80 year old woman with a lump in the breast and back pain.
There is a defect in the upper surface of the anterior end of the left 2nd rib and a larger defect in the posterior border of the right third rib.

Radiology case 4411-3310
The many medical students, to whom I have shown this, all fixate on the calcifications in the spleen. They then notice the calcification in the undersized left kidney and the mid-line calcifications. The absent right hemidiaphragm shadow or right mastectomy are noticed next. The right lower lobe...

Radiology case 454-3310 70 year old woman with known carcinoma of breast. There is a lytic expanding lesion of the metaphysis of the tibia. The endosteal transition seems narrow and the overlying cortex appears intact, but irregularly thinned. The pathology extends to the joint margin, but does not cross it. There...

angulated fracture at the junction of the proximal and middle third of ulna accompained by ANTERIOR dislocation of the radial head
etiology:
* transmission of force thorugh the hand and forearm with the elbow partially flexed
* interosseous ligament "drags" the radius with the distal two-thirds of the ulna
MUGR mnemonic
* Monteggia with...

Morquio's Syndrome
mucopolysaccharidosis (MPS) type IV
* autosomal recessive deficiency of N-acetylgalactosamine-6-sulfatase build up of keratin sulfate
* normal intelligence
* platyspondyly ("universal vertebra plana" = hallmark)
...

# females, middle age
# deposition arthropathy
# bilaterally symmetric involvement of hands
# soft-tissue swelling
# well-circumscribed marginal bony erosions

* most common primary malignant neoplasm of bone
* 50-70y; M:F 2:1
* symptoms: vague bone pain of progressive severity, fever, anemic sxs
* complications: pathologic fractures
* solitary plasmacytoma: solitary osseous focus of MM (uncommon)
x-ray findings:
* loss of bone density - from diffuse marrow involvement
* "punched out" lesions - esp. skull, long bones
*...

Radiology case 418-3452 Female patient aged 50 years with backache and proteinuria. Recent pain in right humerus after a fall.
There are lytic areas in the metaphysis and diaphysis of the right humerus. Similar distributed lytic areas are present in the clavicle, scapula and ribs. The lytic lesions are predominantly in...

Radiology case 48--3452 Clinical presentation: 42 year old male with an 8 month history of increasing back pain. Had been bed-ridden for the last 3 weeks. The serum calcium was markedly elevated.
The plain film view of the pelvis shows extensive patchy bone destruction. The lytic areas undermine the cortex at various...

Multiple Myeloma is a neoplasm of differentiated plasma cells resulting from malignant clonal expansion and overproduction of monoclonal immunoglobulins. Common complications include recurrent bacterial infections, anemia, osteolytic lesions and renal insufficiency. Diagnostic Radiology/Musculoskeletal Imaging/Tumors Basic/Multiple Myeloma From Wikibooks, the open-content textbooks collection