Bone Scan (Subscribe)  

* anaplastic tumors
* reticulum cell sarcoma
* renal cell Ca
* thyroid Ca
* histiocytosis
* neuroblastoma
* multiple myeloma (positive scan usually due to recent or...

Bone scans image physiology injection of a bone seeking compound attached to a radioisotope. The material is laid down in the hydroxyapatite crystal.
The resultant radiation is picked up by a gamma camera, consisting of a circular sodium iodide crystal 40cm in diameter coupled to a number of photomultiplier tubes.
Bone scanning relies...

Bone Scintigraphy (SCAN) 21 cases: Access by Diagnosis
J. Anthony Parker, MD, PhD B. Leonard Holman MD

In patients with knee osteoarthritis. bone scintigraphic abnormalities are strongly associated with knee malalignment and pain, North Carolina-based researchers report in the November issue of the Annals of the Rheumatic Diseases.
Refers to Association of bone scintigraphic abnormalities with knee malalignment and pain Kraus et al. Ann Rheum Dis.2009; 68: 1673-1679

increased activity in:
* active osteomyelitis (90% sensitivity: better than Tc-99m MDP)
* sarcoma
* cellulitis
* septic arthritis
* rheumatoid arthritis
* Paget disease
* metastases (65% sensitivity:...

* overlying atenuation caused by pacemaker, barium, metal cross, wristwatch
* radiation therapy
* local vascular compromise
* early osteomyelitis
* tumor: neuroblastoma
o renal...

Engelmann's disease (progressive diaphyseal dysplasia) Brief history: Thirty-eight-year-old woman with a known history of a skeletal dysplasia. Bone scan images MIR Teaching file case bs109

non-routine localized hot bone lesions:
* Paget's disease
* osteoid osteoma
* fibrous dysplasia
* melorheostosis
generalized:
* hyperparathyroidism
* hematologic disorders
* Paget disease (rare)
* fibrous dysplasia
* renal osteodystrophy

Bone scanning uses a Technetium 99m diphosphonate or polyphosphonate. This becomes fixed to hydroxyapatite in the bone and marks those areas where bone is being laid down. The activity is high at any site where there is a bone reaction to any process or pathology. The diagnosis is made from...

Radiology case 48--3452 Clinical presentation: 42 year old male with an 8 month history of increasing back pain. Had been bed-ridden for the last 3 weeks. The serum calcium was markedly elevated.
The plain film view of the pelvis shows extensive patchy bone destruction. The lytic areas undermine the cortex at various...

Contributor: Christopher J Bennett - National Capital Consortium Paget's disease at osseous scintigraphy Factoid 4755 - Created: 2003-04-24 12:50:56-04 - Modified: 2003-05-04 19:15:37-04 ACR Codes: 4.5 Paget’s disease is characterized by high rates of bone turnover and the formation of abnormal, weak bone. It is extremely common, found in...

Clinical presentation: 80 year old lady with pain in her right hip.
There is increased density of the right hemi-pelvis. The bone dimensions are increased. There is coarsening of the bone architecture with loss of detail. There is protrusio acetabulae, indicating bone softening. ACR-code 448-843

Paget's Disease of Bone. In the bone scan, we see intense uptake in the lower T-spine, the mid L-spine, sacrum, and the sacral wings. The "butterfly" pattern of vertebral involvement suggests Paget's Disease, which affects the entire vertebral body rather than metastatic disease, which predelicts the pedicles. Paget's Disease frequently, but not...

To the best of our knowledge, the bone scintigraphy findings of a case of Morquio's syndrome have never before been published. We present our case report to add to the knowledge we have of this rare disease.
Scintigraphic Features of Morquio's Syndrome: A Case Report Bjoern Kitzing; Kevin C Allman J Med...

Radiology case 456-415 Clinical presentation: Young adult male, who was training as a boxer. He began to develop pains in the right leg and consulted a physician 6 weeks before, but continued with his skipping exercises, jumping more with the right leg than his left.
There is periosteal newbone and sclerosis over...