Radiology - Conditions (Subscribe)  

destruction is widespread and obvious. Close inspection Multiple Myeloma of the largest lesion shows it to be purely lytic, without any matrix or calcification. There are numerous "tear-drop" shaped lytic lesions in the Multiple Myeloma left femur. Pathologic fracture of the neck of the femur can be clearly seen.
For all...

Radiology case 48--6572 Clinical presentation: 52 year old male with anaemia.
There is Splenomegaly. The soft tissue density of the spleen extends to the iliac crest. There is a variable increase in density of the axial skeleton and adjacent ilium with coarsening of the visible bone architecture. The vertebral bodies are involved,...

Radiology case 48--1611 Clinical presentation: 20 year old male with decreasing mobility.
The view shows soft tissue ossification. The thick strands of bone can be seen in psoas and latissimus dorsi. These are not the muscles that might be subject to trauma in patients with neurological motor function abnormalities, whose limbs might...

disease involving the skeletal muscles of the upper extremities, shoulder girdle, neck and GI tract.
* symptoms:
o frontal balding
o testicular atrophy
o...

Fong syndrome, onycho-osteodysostosis
* autosomal dominant
Features:
* abnormal fingernails
* absent/hypoplastic patella
* defects in radial head
* iliac horns (bony processes along posterior surfaces of iliac bones)
* discoloration of iris

Nail-patella syndrome (synonyms: Fong’s disease, Trauner-Rieger syndrome) is a rare autosomal dominant condition.
Clinically the key feature is absent/hypoplastic nails from birth.
• Diagnostic radiographic findings include the following:
o Absent/Hypoplastic patellae (with a tendency to recurrent dislocation)
o Hypoplasia of the radial head or capitellum (leading to subluxation/dislocation)
...

Radiology case 416-3318 Female patient, aged 2 years with an upper abdominal mass.
There are ill-defined lytic areas in the metaphyses and one further area in the diaphysis. The metaphyseal process affects that part of the bone that retains a greater metabolic activity, just proximal to the epiphyseal plate.
There is...

Radiology case 48-3318 Clinical presentation: A child who had had chemotherapy for a previous upper abdominal tumour.
There is patchy bone destruction in the metaphyses and endosteal scalloping of the cortex of the diaphyses of the humeri, giving an irregular appearance.

Radiology case 38--1831 There is scalloping of the posterior margins of the vertebral bodies with a concave outline. There is enlargement of the neural foramina. The contrast of the myleogram fills sacculations of the theca.

Definition Neurofibromatosis type I (NF-1), along with Neurofibromatosis type II (a.k.a. MISME syndrome), Tuberous Sclerosis, Sturge-Weber, and Von Hippel-Lindau compromise the phakomatosis or neurocutaneous syndromes, all of which have neurologic and dermatologic lesions. This grouping is an artifact of an earlier time in medicine, before the distinct genetic basis of each...

aka: alkaptonuria
* autosomal recessive
* excessive homogentisic acid
o no homogentisic acid oxidase
o part of phenylalanine / tyrosine pathway
* alkaptonuria: brown/black urine
* ochronosis: brown/black pigmentation of skin, mucous membranes
* pigment deposition in...

Radiology case 448-4146 31 year old man with pain in both hips and inability to walk, originally from India.
There is distortion and flattening of the heads of both femora. There is lateral migration so that the neck of each femur no longer points to the centre of radius of the...

* multiple enchondromata
* hamartomas of cartilage within bone
* may be limited to one extremity or to extremities of one side
* femur + tibia most often involved
* may degenerate --> chondrosarcoma

ischemic necrosis / osteochondritis of the tibial tuberosity (insertion of patellar tendon, site of traumatic injury)
* ST swelling
* fragmented apophysis with irregularly increased density
* males (75-85%)
* age: 10-15 (boys), 8-13 (girls)
* 25% bilateral

# The medial end of the right clavicle is sclerotic and questionably enlarged.
# The manubrium is unaffected and the sternal-manubrial joint is intact.