Metastasis lytic ca breast LSBU

Description: Radiology case 454-3310 70 year old woman with known carcinoma of breast. There is a lytic expanding lesion of the metaphysis of the tibia. The endosteal transition seems narrow and the overlying cortex appears intact, but irregularly thinned. The pathology extends to the joint margin, but does not cross it. There is no indication of joint effusion.
There is a more subtle loss of bone density in the rest of the metaphysis that extends into the diaphysis. It has the form of a collection of small lytic areas that produces a coarsening of the visible trabecular pattern and a patchy porosis of the cortex in the region of the tibial tuberosity. The visible lower margin and the more distal normal bone density suggests that this is not disuse osteoporosis.