Acquired Hyperostosis Syndrome (Subscribe)  

The acronym SAPHO was introduced in 1987 to unify the various descriptions of a seronegative arthritis associated with skin manifestations and to show synovitis, acne, pustulosis, hyperostosis, and osteitis with and without sterile multifocal osteomyelitis. The etiology of SAPHO syndrome is unknown, an association with infection by semipathogenic bacteria like...

This search was more productive than a search for Acquired Hyperostosis Syndrome but did find a lot of dermatological material

Search String "Acquired Hyperostosis Syndrome"[MAJR] URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&term=%22Acquired+Hyperostosis+Syndrome%22%5BMAJR%5D 111 articles Nov 2006

SAPHO syndrome, representing a constellation of synovitis, acne, palmo-plantar pustulosis, hyperostosis, and osteitis, is now recognized as a distinct medical entity: a reactive infectious osteitis. Genetic, immunological, and bacterial mechanisms are implicated in the development of the disease. Diagnostic problems may arise due to non-complete manifestations of SAPHO: either acne...

SAPHO Syndrome At A Glance SAPHO syndrome is a chronic disorder that involves the skin, bone, and joints. SAPHO is an eponym for the combination of synovitis, acne, pustulosis, hyperostosis, and osteitis. Some researchers feel that the SAPHO syndrome is related to the group of arthritis conditions which typically affect the...

Abstract A middle aged man presented with a 4 year history of painful swelling of both knees and pustular acne on his back. The MRI scan of the knees showed gross synovitis, so did the histopathology of the synovium. A diagnosis of SAPHO syndrome was made and he was...

Definition Synovitis Acne -- commonly involving the face and upper back. Pustulosis -- usually involving the palms of the hands and/or soles of the feet (palmo-plantar pustulosis). Hyperostosis Osteitis SAPHO syndrome is thought to comprise a spectrum of disorders that share some clinical, radiologic and pathologic characteristics. An entity known as...

SAPHO syndrome is thought to comprise a spectrum of disorders that share some clinical, radiologic and pathologic characteristics. An entity known as chronic recurrent multifocal osteomyelitis (CRMO) was first described in 1972. Subsequently in 1978 several cases of CRMO were associated with clinical findings of palmoplantar pustulosis. Since then, a... Uncertain