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SAPHO syndrome

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Location: http://arthritis-research.com/content/pdf/ar2837.pdf

Description: SAPHO syndrome, representing a constellation of synovitis, acne, palmo-plantar pustulosis, hyperostosis, and osteitis, is now recognized as a distinct medical entity: a reactive infectious osteitis. Genetic, immunological, and bacterial mechanisms are implicated in the development of the disease. Diagnostic problems may arise due to non-complete manifestations of SAPHO: either acne and arthritis or acne and anterior wall osteitis with an unclear pustulosis history. The interventional study of Assmann et al. is a significant addition to a long range of publications showing an association of SAPHO with Propionibacterium acnes. Randomized control studies are needed to confirm the effects of antibiotic therapy.
SAPHO syndrome: Is a range of pathogen-associated rheumatic diseases extended? Rozin AP Arthritis Research & Therapy 2009, 11:131

Type: Reference Material
Author/Contact: Rozin AP
Institution: Arthritis Research & Therapy
Primary Subject/Category:

Language: English

Submitted by: admin
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Added: Sun Nov 08 2009