Liposarcoma (Subscribe)  

Medscape The differential diagnosis of a soft-tissue mass includes a variety of benign lesions as well as sarcoma, primary or metastatic carcinoma, melanoma, and lymphoma. There is no distinctive, classic presentation for extremity sarcoma, and chief complaints may vary. It is important to consider the etiology of the neoplasm and any...

US National Institutes of Health. List of therapeutic trials recruiting liposarcoma patients

Liposarcoma is a malignancy of fat cells. In adults, it is the most common soft tissue sarcoma. Liposarcoma normally appears as a slowly enlarging, painless, nonulcerated submucosal mass in a middle-aged person, but some lesions grow rapidly and become ulcerated early.

Liposarcoma risk factors may include Lipomatosis, multiple, hereditary Liposarcoma: Definition(s) via UMLS "A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are...

Liposarcoma occurs in the deep soft tissue of extremities and in the retroperitoneum. It is the most common soft tissue sarcoma and accounts for 20% of all mesenchymal tumors. They are typically large bulky tumors which tend to have multiple satellite lesions extending beyond the gross confines of the tumor....

Two Forms: - low grade myxoid liposarcoma; - most common; - occurs in young adults; - in myxoid liposarcoma, lipoblasts...

Liposarcoma is a malignant tumor that arises in fat cells in deep soft tissue, such as that inside the thigh or in the retroperitoneum. They are typically large bulky tumors which tend to have multiple smaller satellites extending beyond the main confines of the tumor.

Liposarcoma is the most common soft tissue malignancy in adults accounting for at least 20% of all sarcomas in this age group. Myxoid-round cell liposarcoma is a subtype of liposarcoma characterized by the presence of the reciprocal chromosomal translocation t(12;16)(q13;p11). This translocation creates the FUS-DDIT3 chimeric gene. Sánchez-Martín M, González-Herrero I,...

Liposarcoma is one of the least frequent nonrhabdomyosarcoma soft tissue sarcomas that occur in childhood; it comprises less than 5% of all soft tissue sarcomas. Surgical excision is the primary treatment, and prognosis is dependent on histologic subtype and degree of resection. For patients with residual disease, radiotherapy has...

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Illustrated cases