Liposarcoma Wheeless

Description: Two Forms: - low grade myxoid liposarcoma; - most common; - occurs in young adults; - in myxoid liposarcoma, lipoblasts are dispersed in anastomosing capillary framework; - fine reticular vascular pattern; - high grade pleomorphic liposarcoma: - pleomorphic liposarcoma is more common in older patients; - enlarging but painless mass in the buttocks (most common site), proximal thigh, or upper arm is the classic presentation; - more aggresive tumor which tends to invade bone; - have amorphously arranged large vascular lakes; - contains large, pyknotic, bizarre, mononucleated cells in combinatination with immature lipoblasts;