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Ankylosing Spondylitis
[OCOSH Code: D013167 9631008 M45 JD_A_AS]

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A Review of the Pathogenesis of Ankylosing Spondylitis Medscape

Location: http://www.medscape.com/viewarticle/570733

Ankylosing spondylitis (AS) is a chronic, progressive inflammatory rheumatic disease involving primarily the sacroiliac joints and the axial skeleton. The main clinical features are back pain and progressive stiffness of the spine. Oligoarthritis of the hips and shoulders, enthesopathy, and anterior uveitis are common, and involvement of the heart and...
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View Details Visit Resource Review It Rate It Bookmark It Added: Tue Apr 08 2008

Ankylosing Spondylitis PatientPlus

Location: http://www.patient.co.uk/showdoc/40024909/

Ankylosing spondylitis is a chronic seronegative spondyloarthropathy which primarily involves the axial skeleton (e.g. sacroiliitis and spondylitis). The aetiology is unknown but involves the interaction of genetic and environmental factors. The diagnosis is made by combining clinical criteria of inflammatory back pain and enthesitis (inflammation at the site of bone...
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View Details Visit Resource Review It Rate It Bookmark It Added: Tue May 26 2009

Can Structural Damage Be Prevented in Ankylosing Spondylitis Medscape

Location: http://www.medscape.com/viewarticle/706108

Current treatment of ankylosing spondylitis such as non-steroidal anti-inflammatory drugs and tumor necrosis factor (TNF)-blockers have shown a good efficacy on sign and symptoms. However, it is less clear whether and how structural damage, determined mainly by new bone formation, can be prevented. Recent progress of the research addressing this...
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View Details Visit Resource Review It Rate It Bookmark It Added: Wed Aug 26 2009

Spinal anesthesia by mini-laminotomy for a patient with ankylosing spondylitis who was difficult to anesthetize CORR Open Access

Location: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974874

Background Orthopaedic surgeons frequently encounter patients with ankylosing spondylitis who would benefit from various types of lower limb operations; however, some of these patients present challenges for anesthesiologists.
Case Description We report the case of a 65-year-old patient with a fractured femoral component 30 years after a cemented THA. The patient had severe...
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View Details Visit Resource Review It Rate It Bookmark It Added: Mon Apr 18 2011

What do biomarkers tell us about the pathogenesis of ankylosing spondylitis?

Location: http://arthritis-research.com/content/pdf/ar2565.pdf

Biomarkers may provide information that promotes understanding of prognosis, disease activity, and pathogenesis in ankylosing spondylitis. Biomarkers reflecting disease activity (metallo- proteinase-3) and inflammatory lesions on magnetic resonance imaging predict new bone formation and are ameliorated by anti- tumor necrosis factor therapy, yet this treatment may not prevent new bone...
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View Details Visit Resource Review It Rate It Bookmark It Added: Sun Jan 11 2009