Osteopoikilosis MedPix

Description: Enostoses (bone islands) form when endochondral ossification proceeds normally, but the mature bony trabeculae fail to properly remodel. Osteopoikilosis (osteopathia condensans disseminata, or “spotted bone disease�), like enostosis or osteopathia striata, is typically an autosomal dominant, asymptomatic disorder characterized by an abnormality in the endochondral bone maturation process. Osteopoikilosis results in numerous rounded or oval, 2-10mm enostoses that appear in childhood and persist throughout life.