diastrophic dwarfism CHORUS

Description: short-limbed dwarfism ("diastrophic" means twisted, thus scoliosis)
x-ray features:
* short flared metaphyses with flattened epiphyses in tubular bones of extremities
* equinovarus deformity of feet -- major joints subluxed
* spine: kyphoscoliosis with gradual decrease in interpediculate distance toward caudal end of L-spine
* hands
o "hitch-hiker's thumb" - widely abducted
o hypoplastic first metacarpal
o other metacarpals too broad, esp. at growing end
o carpal bones with too many centers ossified