Orthopedics > OCOSH Classification > Orthopaedic Procedures > Arthroplasty > Replacement Arthroplasty > Hip Replacement Arthroplasty > DVT Prophylaxis in Hip & Knee Replacement Surgery Controversies in 2008 COA

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DVT Prophylaxis in Hip & Knee Replacement Surgery Controversies in 2008 COA

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Location: http://www.coa-aco.org/coa-bulletin/issue-83/dvt-prophylaxis-in-hip-a-knee-replacement-surgery-j-wad ...

Description: Routine thromboprophylaxis following elective hip and knee replacement surgery remains a controversial topic. No one disputes that patients undergoing these surgical procedures are at risk for deep vein thrombosis. The combination of stasis, endothelial wall injury and hypercoagulability are almost routine following this type of hip and knee surgery. It is because of the prevalence of deep vein thrombosis in these patients that they are frequently selected for study in large clinical trials examining the efficacy of various antithrombotic agents.
Much of the discord surrounding routine thromboprophylaxis for hip and knee replacement surgery relates to the clinical trials studying these patients. They report a high incidence of venographically demonstrated thrombi in patients days or weeks following the surgical procedure in question. Only a tiny fraction of these patients with venographically proven thrombi are in fact symptomatic and an even smaller number of patients in these large studies ever develop symptomatic pulmonary embolism proven by diagnostic imaging.
James P. Waddell, M.D., FRCSC COA Bulletin Issue 83 2008

Type: Reference Material
Author/Contact: James P. Waddell, M.D., FRCSC
Institution: COA
Primary Subject/Category:

Language: English

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Added: Wed Jul 01 2009