Melorheostosis OMIM

Description: CLINICAL FEATURES This disorder is similar to Ollier disease, Albright polyostotic fibrous dysplasia, Sturge-Weber syndrome, Klippel-Trenaunay-Weber syndrome, and others in which no mendelian basis has been established. The designation combines roots meaning limb, flow, and bone. The bones of the limbs (but not limited to these) show asymmetrical bands of sclerosis in a flowing pattern. The changes may extend across joints. The soft tissues overlying the bones are also sclerotic.