Polyostotic Fibrous Dysplasia DiseasesDatabase

Description: Osteitis Fibrosa Disseminata: "A disease of bone marked by thinning of the cortex and replacement of bone marrow by gritty fibrous tissue containing bony spicules, producing pain, disability, and gradually increasing deformity. Only one bone may be involved (FIBROUS DYSPLASIA, MONOSTOTIC) or several (FIBROUS DYSPLASIA, POLYOSTOTIC). (From Dorland, 28th ed)" 2 synonyms or equivalents were found. Polyostotic fibrous dysplasia aka/or McCune-Albright syndrome may cause or feature Miscellaneous syndromes Bone lysis Hyperostosis Pathological fracture Symptoms and Signs Café au lait spots Facies abnormality Precocious puberty X-ray abnormalities Erlenmeyer flask deformity Endocrine conditions Cushing's syndrome Hyperthyroidism Inflammatory conditions Osteitis may be a risk factor for Endocrine conditions Pituitary tumour (growth hormone secreting) Neoplastic conditions Phaeochromocytoma