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2011 Healing of Long-term Frozen Orthotopic Bone Allografts is not Affected by MHC Differences Between Donor and Recipient CORR Open Access
It remains unclear whether differences in the major histocompatibility complex (MHC) influence incorporation of bone allografts and their subsequent biologic performance.
We detected no alloantibody production to graft MHC-I antigens, and found no differences between syngeneic and MHC mismatched grafts in terms of remodeling with host bone, graft healing, and mechanical strength.
Mismatches for MHC antigens do not seem to play a decisive role in healing of long-term, deep-frozen bone allografts.
Healing of Long-term Frozen Orthotopic Bone Allografts is not Affected by MHC Differences Between Donor and Recipient.
ReikerÃ¥s O, Reinholt FP, ZinÃ¶cker S, Shegarfi H, Rolstad B.
Clin Orthop Relat Res. 2011 May;469(5):1479-86 (full text)
Type: Reference Material
Author/Contact: ReikerÃ¥s et al
Submitted by: admin
Added: Wed May 04 2011