Growth hormone as concomitant treatment in severe fibromyalgia associated with low IGF-1 serum levels

Description: There is evidence of functional growth hormone (GH) deficiency, expressed by means of low insulin-like growth factor 1 (IGF-1) serum levels, in a subset of fibromyalgia patients. The efficacy of GH versus placebo has been previously suggested in this population. We investigated the efficacy and safety of low dose GH as an adjunct to standard therapy in the treatment of severe, prolonged and well-treated fibromyalgia patients with low IGF-1 levels.
Growth hormone as concomitant treatment in severe fibromyalgia associated with low IGF-1 serum levels. A pilot study. Cuatrecasas G, Riudavets C, Güell MA, Nadal A. BMC Musculoskelet Disord. 2007 Nov 30;8:119.