van der Woude Syndrome eMedicine

Description: This article is primarily about the treatment of the orofacial feature (cleft lip and palate). It mentions that popliteal pterygium is associated with this condition. Symptoms of van der Woude syndrome have been seen in individuals with popliteal pterygium syndrome, which has also been linked to mutations in the same gene. These 2 entities are believed to be allelic variants of the same condition.
It follows that individuals with Pterygium should be examined for orofacial abnormalities.
Gregory P Conners, MD Updated: Apr 16, 2009