2009 Colchicine PatientPlus

Description: This is an anti-gout agent. Mode of action
* It acts by inhibiting the production of tubulin, a protein essential for the development of microtubules.
* These form the spindles essential for cell division, intracellular transport of vesicles and proteins, flagella reassembly, and the ameboid motility of cells.
* In this way colchicine inhibits both the migration of macrophages/leukocytes and phagocytosis - reducing the inflammation and pain of gout.
The original page containing the above introduction has been withdrawn and the current page is more patient oriented (OWL Editor)