2007 Histomorphological study of the spinal growth plates from the convex side and the concave side in adolescent idiopathic scoliosis

Description: Shoufeng Wang , Yong Qiu , Zezhang Zhu , Zhaolong Ma , Caiwei Xia and Feng Zhu Journal of Orthopaedic Surgery and Research 2007, 2:19
Asymmetrical growth of the vertebrae has been implicated as one possible etiologic factor in the pathogenesis of adolescent idiopathic scoliosis. The longitudinal vertebral growth derives from the endochondral ossification of the vertebral growth plate. In the present study, the growth plates from the convex and concave side of the vertebrae were characterized by the method of histology and immunohistochemistry to evaluate the growth activity, cell proliferation, and apoptosis.