Author: Wilfred CG Peh, MBBS, MHSM, MD, FRCPE, FRCPG, FRCR, Clinical Professor, Faculty of Medicine, National University of Singapore; Senior Consultant Radiologist, Programme Office, Singapore Health Services
Contents - Introduction Differentials Radiograph CT Scan MRI Nuclear Medicine Intervention Pictures Bibliography
Ankylosing spondylitis is a distinct disease entity characterized by inflammation of multiple articular and para-articular structures, frequently resulting in bony ankylosis. The term ankylosing is derived from the Greek word ankylos, meaning stiffening of a joint, while spondylos means vertebra. Spondylitis refers to inflammation of one or more vertebrae. Ankylosing spondylitis usually is classified as a chronic and progressive form of seronegative arthritis. Ankylosing spondylitis has a predilection for the axial skeleton, affecting particularly the sacroiliac and spinal facet joints and the paravertebral soft tissues. Extraspinal manifestations of the disease include peripheral arthritis, iritis, pulmonary involvement, and systemic upset.