Rhabdomyolysis

Description: Rhabdomyolysis (RDM) is a disorder causing injury to muscle, particularly the sarcolemma of skeletal muscle. The process may be precipitated by acute traumatic injury (burn, crush, and exertion), disease (alcoholism), disorders of lipid and carbohydrate metabolism, drugs (Hydroxymethylglutaryl–CoA Reductase Inhibitors— Statins [HMG-CoA]), and other various muscle membrane and ion channel dysfunctions. RDM is sometimes used interchangeably when discussing the process of myoglobinuria.