Multiple Myeloma Wheeless

Description: Discussion: - myeloma is malignant tumor of plasma cells arising from a single clone; - multiple myeloma accounts for> 40% of primary malignant tumors of bone. - it is most common malignant primary tumor of bone - may arise as single intraosseous tumor but more often it develops as multiple painful lesions throughout skeleton (multiple myeloma); - whether from single or multiple sites, myeloma spreads to involve virtually entire bone marrow which eventually produces death