Osteogenesis Imperfecta POSNA Study Guide

Description: Objectives 1. Describe the basic connective tissue fault of bone in individuals with osteogenesis imperfecta 2. Describe the spectrum of severity of the clinical spectrum of osteogenesis imperfecta 3. Describe the natural history -both in regard to function and survival -of patients with osteogenesis imperfecta 4. Discuss the orthopaedic problems associated with osteogenesis imperfecta and present approaches to these problems 5. Describe present pharmacologic systemic approaches undergoing evaluation for osteogenesis imperfecta 6. Describe the genetic pattern of osteogenesis imperfecta