Short-limb dwarf osteogenesis imperfecta

Description: In another fetus at 32 weeks with the same diagnosis (Film 3), there is a smaller abdomen than head (Scans 1 and 2) consistent with growth retardation. The chest (Scan 3) is even smaller, and the limb (right femur shown in Scan 4) is severely foreshortened, bowed and demineralized. Film 4 is the radiograph of the stillborn fetus. The differential diagnosis when poor mineralization is evident would also include a rarer condition, also lethal, called hypophosphatasia.