osteogenesis imperfecta Type III MedPix

Description: osteogenesis imperfecta (OI) is a group of genetic disorders that primarily result in the improper formation of type I collagen. These disorders range in severity from lethality in utero to extremely mild disease resulting in very little difference phenotypically than the unaffected population. The unifying clinical feature of this group of disorders is generalized osteopenia resulting in multiple pathological fractures.