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Necrotizing Fasciitis

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Location: http://en.wikibooks.org/wiki/Diagnostic_Radiology/Musculoskeletal_Imaging/Infection/Necrotizing_fasc ...

Description: Definition Necrotizing fasciitis is a rare, often fulminant, rapidly progressive infectious process primarily involving the fascia and subcutaneous tissue. The pathophysiology involves the rapid spread of infection along the fascial planes, fascial necrosis and thrombosis of the subcutaneous blood vessels, leading to cutaneous gangrene. Approximately 500 to 1500 cases reported annually in the US. The most often associated comorbities are diabetes mellitus and peripheral vascular disease. It is most often peripheral, involving the lower limb. Delay to diagnosis is one of the most prominent predictors of mortality (along with diabetes). Prognosis for necrotizing fasciitis depends heavily on early recongnition and determination of the extent of necrosis in the preoperative planning. Clinical studies are lacking that compare different imaging modalities to the gold standard of fasciotomy. These series are typically small and only look at a handful of cases. Diagnostic Radiology/Musculoskeletal Imaging/Infection/Necrotizing fasciitis From Wikibooks, the open-content textbooks collection

Type: Reference Material
Author/Contact: Open Authorship
Institution: Wikibooks
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Language: English

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Added: Fri Dec 01 2006
Last Modified: Thu Jul 12 2007