Giant Cell Tumor of Bone Wheeless

Description: Discussion: - a common benign but locally aggressive lesion of unknown etiology; - occurs chiefly in men between 20-50 yrs (after epiphyseal closure); - tumor is expansile lytic lesion that involves the epiphysis & metaphysis; - tumor may enlarge to occupy most of epiphysis & adjacent metaphysis; - tumor may erode & penetrate subchondral bone, articular cartilage, & cruciate ligaments;