Ectrodactyly ectodermal dysplasia and cleft lip and palate 3 OMIM

Description: ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 3; EEC3
Alternative titles;
EEC SYNDROME 3
The features of EEC syndrome are ectrodactyly of hands and feet, ectodermal dysplasia, and cleft lip/palate. Maas et al. (1996) found great variability in the clinical manifestations of EEC in affected members of a large Dutch kindred.
Kosaki et al. (2008) reported a Japanese infant with split hand-foot malformation and cleft lip and palate. He had underdevelopment of the central digital rays of both hands and feet, sparse hair, and thin and dry skin.