OWL: OCOSH Classification/Systemic Disorders

2011 Distinguishing fibromyalgia from rheumatoid arthritis and systemic lupus in clinical questionnaires

Friend and Bennett — 2011-04-13 00:15:00 GMT

Conclusions A combination of 2 questions ("tenderness to touch" and "difficulty sitting for 45 minutes") plus pain in the lower back, neck, hands and arms, may be useful in the construction of clinical questionnaires aimed at patients with musculoskeletal pain. This combination provided a correct diagnosis in 97% of subjects, with only 7 of 253 subjects misclassified.
Distinguishing fibromyalgia from rheumatoid arthritis and systemic lupus in clinical questionnaires: an analysis of the revised fibromyalgia impact questionnaire (FIQR) and its variant the symptom impact questionnaire (SIQR) along with pain locations Ronald Friend and Robert M Bennett Arthritis Research & Therapy 2011, 13:R58

Congenital and Metabolic Diseases

2006-11-29 00:15:00 GMT

There is no single unifying trait for these disorders. Some have their genetic defect well characterized. Others are still waiting for the discovery of the gene or genes which are damaged. The diagnosis requires careful clinical laboratory evaluation and may require testing for enzymes that are only available in research laboratories. Biopsy diagnosis may play an important role, not only in establishing the diagnosis, but providing fresh tissue for molecular and enzyme studies. Acrodermatitis Enteropathica Alagille Syndrome Alkaptonuria (Ochronosis) Alpha-1-Antitrypsin Deficiency Alport Syndrome Amyloid Bannayan-Zonana Syndrome Canavan Disease Common Variable Immunodeficiency Cowden Syndrome Cystic Fibrosis Diabetes Insipidus Down Syndrome (Trisomy 21) Ectodermal Dysplasia Ehlers-Danlos Disease Fabry Disease Fucosidosis Galactosemia Gaucher Disease Glucagonoma Gout Juvenile Hyaline Fibromatosis (Murray-Puretic Syndrome) Mucopolysaccharidoses Necrolytic Migratory Erythema Neurofibromatosis Ochronosis (Alkaptonuria) Osteogenesis Imperfecta Porphyria Proteus Syndrome Pseudogout Pseudoporphyria Refsum's Disease Restrictive Dermopathy Retinitis Pigmentosa Rubinstein-Taybi Syndrome Scurvy (Vitamin C Deficiency) Shwachman-Diamond Syndrome Syndrome of Inappropriate Anti-Diuretic Hormone (SIADH) Tuberous Sclerosis von Hippel-Lindau Disease Williams Syndrome

Musculoskeletal involvement in systemic lupus erythematosus Orthopaedia

Not Available — 2009-07-07 00:15:00 GMT

Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease associated with antinuclear antibody (ANA) production. Clinical manifestations of SLE can involve nearly every organ system, including the skin, heart, lungs, kidneys, nervous system, blood, and musculoskeletal system. Patients with SLE may initially present to the orthopedist because joint pain is one of the earliest and most common symptoms of SLE, occurring in 50-95% of patients.