Ectodermal Dysplasia (Subscribe)

Images of patients with ED

Ectodermal dysplasia may be caused by or feature of the following Congenital conditions Papillon Lefevre syndrome Mendelian inherited conditions Hypohidrotic X-linked ectodermal dysplasia Olmsted syndrome Autosomal dominant conditions Acro-dermato-ungual-lacrimal-tooth syndrome Hay-Wells syndrome Hidrotic ectodermal dysplasia Jadassohn-Lewandowsky syndrome Rapp-Hodgkin ectodermal dysplasia syndrome Witkop's syndrome Autosomal recessive conditions Margarita Island ectodermal ...

Review by dermatologist. Article by Kara N Shah, MD, PhD

Definition Return to top Ectodermal dysplasia is a hereditary condition characterized by abnormal development of the skin, hair, nails, teeth, and sweat glands. Highly Reputable

McGrath et al. (1997, 1999) described a boy with a unique skin disorder comprising trauma-induced skin fragility and congenital ectodermal dysplasia affecting hair, nails, and sweat glands. The proband reported by McGrath et al. (1997) was a 6-year-old boy with unrelated parents. There was no family history of skin blistering or other significant abnormalities. At birth, all of his skin was lobster pink, with blistering on the soles. Over the first 48 hours, he developed more severe blistering ...

Ectodermal Dysplasia (ED) is not a single disorder, but a group of closely related conditions. More than 150 different syndromes have been identified. The Ectodermal Dysplasias are heritable conditions in which there are abnormalities of two or more ectodermal structures such as the hair (tends to be very thin and sparse),teeth (absent, pointed or conical), nails, sweat glands (little or no sweating), cranial-facial structure, the eyes, digits and other parts of the body. Each combination of ...

Ectodermal dysplasia is not a single disorder, but a group of closely related conditions. More than 150 different syndromes have been identified. Ectodermal dysplasias are described as "heritable conditions in which there are abnormalities of two or more ectodermal structures such as the hair, teeth, nails, sweat glands, cranial-facial structure, digits and other parts of the body."

Ectrodactyly-ectodermal dysplasia-cleft syndrome (EEC) is an autosomal dominant disorder characterized by the triad of ectrodactyly, ectodermal dysplasia, and facial clefting (Celli, Duijf, Hamel, et al. 1999). Other features noted in association with EEC include vesicoureteral reflux, recurrent urinary tract infections (Ramirez, Lammer, 2004), obstruction of the nasolacrimal duct (Peterson-Falzone, Hardin-Jones, Karnell, 2001), decreased pigmentation of the hair and skin, missing or abnormal ...

Hypohidrotic ectodermal dysplasia is one of about 150 types of ectodermal dysplasia in humans. Before birth, these disorders result in the abnormal development of structures including the skin, hair, nails, teeth, and sweat glands. Most people with hypohidrotic ectodermal dysplasia have a reduced ability to sweat (hypohidrosis) because they have fewer sweat glands than normal or their sweat glands do not function properly. Sweating is a major way that the body controls its temperature; as ...

Rare Diseases in Sweden Hypohidrotic ectodermal dysplasia belongs to the group of diseases known as ectodermal dysplasias. Alternative names for the disorder are anhidrotic ectodermal dysplasia (EDA I) and Christ-Siemens-Touraine syndrome. Hypohidrotic ectodermal dysplasia was described as early as 1848 by British physician J. Thurnam. There are more than 150 rare, hereditary types of ectodermal dysplasia, which affect the teeth, sweat glands, skin and hair. The most common form of the ...

eMedicine article by Suguru Imaeda, MD, Chief of Health Services Dermatology, Clinical Associate Professor, Department of Dermatology, Yale University School of Medicine Musculoskeltal manifestations - Failure to thrive Metaphyseal widening Spurs of the long bones Wormian bones in the sagittal and lambdoid sutures

This searches the NCBI site for Ectodermal Dysplasia. The early returns are mainly from the OMIM site detailing individual genetic conditions with ED. Reference to articles in the literature and other NCBI databases are also included URL http://www.google.ca/search?hl=en&lr=&q=+site:www.ncbi.nlm.nih.gov+Ectodermal+dysplasia

Ectodermal dysplasia is not a single disorder. It is a group of heritable disorders causing the hair, teeth, nails and glands to develop and function abnormally. More than 100 different ED syndromes have been described