Sarcoid (Subscribe)  

This case is presented because of the infrequency of osteosclerotic sacroidosis and because osteosclerotic lesions can easily be confused with metastatic bone cancer or lymphoma.
Abdelwahab IF, Norman A. AJR Am J Roentgenol. 1988 Jan;150(1):161-2. full text

Orthopaedic Pathology ch 5 p 233 By Vincent J. Vigorita, Bernard Ghelman, Douglas Mintz
Section on Granulomatous infection of bone and joints

Definition Sarcoidosis is an inflammatory disorder characterized by the formation of noncaseating granulomas in tissues without other known cause for granulomatous disease. The disease has a diversity of clinical manifestations, most commonly affecting the lungs, skin, lymph nodes, and eyes, but can involve any organ system, including the musculoskeletal system. Diagnostic Radiology/Musculoskeletal...

The basic pathological finding in sarcoidosis is a noncaseating granuloma that is formed in response to an exaggerated immune reaction mediated by T-helper cells. The etiology is unknown, although increased immunoglobulin M (IgM) and hyperglobulinemia against various infectious agents are present.
Ramy Yakobi, MD, MBA 2009

Although sarcoidosis most commonly involves the lungs, it can affect nearly any organ system, including the lymph nodes,1 eyes, ears,2 skin, liver, spleen, kidneys, bone, joints, nervous system, and heart. Granulomas mediate disease by compressing tissues, secreting cytokines that provoke constitutional symptoms, recruiting inflammatory cells whose products injure local...

Use the "Create Bibliography" link or copy and paste the search string below to run a PubMed search for sarcoidosis in major orthopaedic English language journals. "Sarcoidosis"[Majr:NoExp] (jrid22024 OR jrid2275 OR jrid2208 OR jrid32471 OR jrid3046 OR jrid1981 OR jrid22800 OR jrid22785 OR jrid3221 OR jrid6314 OR jrid20148 OR jrid3758 OR...

Sarcoidosis is a systemic disease commonly affecting lung, skin, or eye. Sarcoidosis involved with osseous structures occurs in approximately 5% of patients, usually involving small bones. Spinal sarcoidosis is extremely rare. The authors report on a man in whom examination of a subclavicular lymph node biopsy specimen and its spinal...