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A sarcoma originating in bone-forming cells, affecting the ends of long bones. [OCOSH Code: D012516 307576001 M9180/3 OO_CTN_BN_OSC]

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Juxtacortical Osteosarcoma (9)
A form of osteogenic sarcoma of relatively low malignancy, probably arising from the periosteum and initially involving cortical bone and adjacent connective tissue. It occurs in middle-aged as well as young adults and most commonly affects the lower part of the femoral shaft.
MeSH Search Term "Osteosarcoma, Juxtacortical"[mesh]
ICD-10 Code M9190/3 Juxtacortical osteosarcoma
SNOMED-CT Term Parosteal osteosarcoma (morphologic abnormality) Concept ID: 128918008
Synonyms - Juxtacortical osteosarcoma
OCOSH Code: D018217128918008 M9190/3 OO_CTN_BN_OSC_J

Resources

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Chemotherapy Plus Muramyl Tripeptide Improves Osteosarcoma Survival

Location: http://www.medscape.com/viewarticle/570128

The addition of muramyl tripeptide (MTP) to conventional chemotherapy for the treatment of osteosarcoma reduces mortality by about 30%, according to findings from long-term follow-up of a phase III trial.
Medscape summary of Meyers et al J Clin Oncol 2008;26:633-638.
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View Details Visit Resource Review It Rate It Bookmark It Added: Sun Mar 30 2008

Classic Osteogenic Sarcoma TumorLibrary

Location: http://www.tumorlibrary.com/case/list.jsp?diagnosis=Osteogenic+sarcoma%2C+classic&order=diagnosis+AS ...

Illustrated cases of osteosarcoma. See also on this site -
Osteogenic sarcoma arising from a non-ossifying fibroma
Osteogenic sarcoma pseudotumor (Brown tumor of hyperparathyroidism)
Osteogenic sarcoma pseudotumor (Caffey's disease)
Osteogenic sarcoma pseudotumor (Giant bone island)
Osteogenic sarcoma pseudotumor (Ossifying compartment syndrome)
Osteogenic sarcoma pseudotumor (Osteogenesis imperfecta)
Osteogenic sarcoma pseudotumor (Pseudotumor of hemophilia)
Osteogenic sarcoma pseudotumor (Stress fracture)
Osteogenic sarcoma...
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View Details Visit Resource Review It Rate It Bookmark It Added: Mon Jun 07 2010

Classic Osteosarcoma eMedicine Radiology

Location: http://www.eMedicine.com/radio/topic504.htm

Osteosarcoma is the most common primary malignant tumor of bone, excluding plasma cell myeloma. Classic, or conventional, osteosarcoma represents the most common variant of osteosarcoma, accounting for approximately 75% of all lesions. Osteosarcoma can affect any bone and is treated by a combination of surgical excision and chemotherapy.
Synonyms and related...
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View Details Visit Resource Review It Rate It Bookmark It Added: Sun Mar 30 2008

Classic Osteosarcoma Wheeless

Location: http://www.wheelessonline.com/ortho/classic_osteosarcoma

Discussion: - malignant tumor of bone in which neoplastic osteoid is produced by a proliferating spindle cell stroma; - most common primary malignant bone tumor of mesenchymal derivation; - arises in adolescents & affects males slightly more often...
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View Details Visit Resource Review It Rate It Bookmark It Added: Wed Mar 28 2007

Current Concepts on the Surgical and Medical Management of Osteosarcoma Medscape

Location: http://www.medscape.com/viewarticle/579883

Although advances have been made in both surgical and medical management of patients with osteosarcoma, the overall survival of patients with osteosarcoma has remained constant, with no substantial improvement in the past 15 years. Advances in imaging have had a substantial impact on surgical planning and staging. These advances have,...
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View Details Visit Resource Review It Rate It Bookmark It Added: Thu Oct 02 2008

Low-Grade Central Osteosarcoma eMedicine Orthopedics

Location: http://www.emedicine.com/orthoped/topic512.htm

Osteosarcoma of bone is a high-grade tumor with a long-term survival rate of 60-85%. Several variants of osteosarcoma exist. High-grade variants include telangiectatic osteosarcoma, small-cell osteosarcoma, high-grade surface osteosarcoma, and secondary osteosarcoma. Other variants, such as low-grade central osteosarcoma, parosteal osteosarcoma, and periosteal osteosarcoma, are less aggressive entities with a...
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View Details Visit Resource Review It Rate It Bookmark It Added: Mon Apr 07 2008

Orthopedic Surgery Options for the Treatment of Primary Osteosarcoma Medscape

Location: http://www.medscape.com/viewarticle/568597

Osteosarcoma is the most common malignant primary neoplasm of bone. Orthopedic procedures are essential components in the multidisciplinary treatment of osteosarcoma. Limb-salvaging procedures offer adequate disease control comparable to the results obtained by amputations. This review discusses the advantages and disadvantages of the various types of amputations and the limb-salvaging...
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View Details Visit Resource Review It Rate It Bookmark It Added: Sun Mar 30 2008

Osteosarcoma

Location: http://en.wikibooks.org/wiki/Diagnostic_Radiology/Musculoskeletal_Imaging/Tumors_Basic/Osteosarcoma

Osteosarcoma is the most common malignant primary bone tumor. Osteosarcoma tends to occur in children and young adults typically 10-25 or 30 years of age. Osteosarcomas also tend to occur in patients in the sixth decade, likely related to malignant degeneration of Paget's disease. It is said that they tend...
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View Details Visit Resource Review It Rate It Bookmark It Added: Sat Dec 02 2006

Osteosarcoma Doctors Doctor

Location: http://www.thedoctorsdoctor.com/diseases/bone_osteosarcoma.htm

This is one of the most common primary bone tumors usually presenting within the first two decades of life. It presents in long bones during periods of the most active bone growth. It most commonly presents with pain and soft tissue swelling of 1-8 months duration. Surprisingly, pathologic fractures are...
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View Details Visit Resource Review It Rate It Bookmark It Added: Sat Jul 07 2007

Osteosarcoma eMedicine Orthopedics

Location: http://www.eMedicine.com/orthoped/topic531.htm

This article focuses on high-grade intramedullary osteosarcoma (also referred to as simply osteosarcoma), including its classic osteoblastic form and its fibroblastic and chondroblastic forms. Osteosarcoma is the most common malignant bone tumor.1, 2 This disease is thought to arise from primitive mesenchymal bone-forming cells, and its histologic hallmark is the...
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View Details Visit Resource Review It Rate It Bookmark It Added: Sun Mar 30 2008

Osteosarcoma eMedicine Pediatrics

Location: http://www.eMedicine.com/ped/topic1684.htm

Osteosarcoma is the third most common cancer in adolescence, occurring less frequently than only lymphomas and brain tumors. It is thought to arise from a primitive mesenchymal bone-forming cell and is characterized by production of osteoid. The mainstay of therapy is removal of the lesion. Limb-sparing procedures can often be...
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Osteosarcoma femur LSBU

Location: http://myweb.lsbu.ac.uk/dirt/museum/444-3221.html

Radiology case 444-3221 5 year old boy with with swelling of the right thigh.
The density of the diaphysis is expanded to an oval by dense thickening of the bone with a centre of radius in mid-diaphysis. There is an additional adjacent soft tissue mass, which has displaced normal muscles. The...
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View Details Visit Resource Review It Rate It Bookmark It Added: Thu Jan 31 2002

Osteosarcoma humerus LSBU

Location: http://myweb.lsbu.ac.uk/dirt/museum/415-3221.html

Radiology case 415-3221 16 year old girl with painful swollen right shoulder.
There is a reduced bone density in the proximal metaphysis and the fusing epiphysis of the right humerus. The endosteal margin of the lesion in the diaphysis is ill-defined with a wide zone of transition between normal and abnormal...
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View Details Visit Resource Review It Rate It Bookmark It Added: Thu Jan 31 2002

Osteosarcoma knee LSBU

Location: http://myweb.lsbu.ac.uk/dirt/museum/451-3221.html

ACR-code 451-3221 14 year old girl with pain and swelling above the right knee.
The skeleton is immature. There is expansion and increased density of the distal end of the right femur. The centre of radius of the tumour is in the distal femoral metaphysis. There is a soft tissue...
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Osteosarcoma knee LSBU

Location: http://myweb.lsbu.ac.uk/dirt/museum/454-3221.html

Radiology case 454-3221 19 year old male with pain in the knee.
There is a lytic area which lies on the medial side of the proximal metaphysis of the right tibia. The lesion is not well demarcated over its whole boundary. The endosteal margin has a wide zone of transition between...
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View Details Visit Resource Review It Rate It Bookmark It Added: Thu Jan 31 2002

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