Muscular Dystrophies (Subscribe)  

Objectives
1. Describe the clinical features of Becker muscular dystrophy, including age at onset, and physical findings at the time the dystrophy becomes clinically apparent
2. Describe the genetic origin of Becker muscular dystrophy
3. Describe the natural history of Becker muscular dystrophy
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is X-linked recessive dystrophy that shares many of the features of DMD, including pseudohypertrophy of muscles; - main clinical difference is that the course is more protracted; - patients are usually able to walk as late as early adulthood and often live into their...

Congenital muscular dystrophy is defined as the presence of weakness or hypotonia at birth, contractures before 6 months of age, and dystrophy on muscle biopsy. It can affect both males and females, can be present with and without central nervous system involvement, and is not associated with a disorder of...

Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy affecting 1 in 3500 boys born worldwide. Although the name Duchenne is inextricably linked to the most common childhood muscular dystrophy, it was Gowers who recognized Sir Charles Bell for providing the first clinical description of Duchenne dystrophy in his...

Peter B Kang , Chris A Feener , Elicia Estrella , Marielle Thorne , Alexander J White , Basil T Darras , Anthony A Amato and Louis M Kunkel
BMC Musculoskeletal Disorders 2007, 8:115
There is a marked variation in clinical phenotypes that have been associated with mutations in FKRP,...

The earliest descriptions of limb-girdle weakness are ascribed to Leyden1 and Möbius2 in 1876 and 1879, respectively. They described adult patients with a pelvic and femoral distribution of weakness and atrophy with a benign course. In 1884, Erb characterized a juvenile form of proximal muscle weakness.3 Erb's patient had...

limb-girdle muscular dystrophy encompasses a wide variety of clinical diseases;
- characterized by weakness of the shoulders and hips with weakness of the distal muscles of the limbs in more severely affected patients
Notes on Clinical Findings, Labs, EMG, Treatment

Objectives
1. Describe clinical symptoms, mode of genetic transmission, and age of onset of limb-girdle muscular dystrophy
2. Describe the usual patterns of weakness in the limb-girdle dystrophies

Muscular dystrophy (MD) is a collective group of inherited noninflammatory but progressive muscle disorders without a central or peripheral nerve abnormality. The disease affects the muscles with definite fiber degeneration but without evidence of morphologic aberrations.
Synonyms and related keywords: MD, dystrophinopathies, Duchenne muscular dystrophy, Duchenne MD, Becker muscular dystrophy,...

Muscular dystrophy (MD) is a collective group of inherited noninflammatory but progressive muscle disorders without a central or peripheral nerve abnormality. The disease affects the muscles with definite fiber degeneration but without evidence of morphologic aberrations.
Twee Do, MD 2009

Notes on Muscular Dystrophies - Duchenne, Becker, Myotonic Dystrophy, Spinal Muscular Atrophy, Juvenile Dermatomyositis, Guillain Barre