Knee Osteoarthritis (Subscribe)  

Young patients with early osteoarthritis wishing to remain functionally active have limited treatment options. Existing studies examining the use of autologous chondrocyte implantation (ACI) have included patients with early degenerative changes; however, none specifically investigated the outcome of ACI with this challenging problem.
At 5 years postoperatively, 92% of patients were...

This review highlights recent research findings, including their clinical application, for insoles and footwear in knee osteoarthritis. In particular, it examines their effect on knee load, osteoarthritis symptoms and disease progression.
Rana S Hinman; Kim L Bennell Curr Opin Rheumatol. 2009;21(2):164-170

In patients with knee osteoarthritis. bone scintigraphic abnormalities are strongly associated with knee malalignment and pain, North Carolina-based researchers report in the November issue of the Annals of the Rheumatic Diseases.
Refers to Association of bone scintigraphic abnormalities with knee malalignment and pain Kraus et al. Ann Rheum Dis.2009; 68: 1673-1679

Conclusions This study identified speciality-related variability in some aspects of the management of knee OA. The clinical profile of patients with knee OA differed between GPs and RHs.
Comparison of general practitioners and rheumatologists' prescription patterns for patients with knee osteoarthritis Pascal Richette , Pascal Hilliquin , Philippe Bertin , Paolo Carni ,...

Coexisting depression is an independent predictor of pain among people with radiographic evidence of mild to moderate osteoarthritis of the knee, researchers in South Korea have found. "The contribution of comorbid depression to knee osteoarthritis symptoms [KOAS] is almost equal to that of radiographic severity," senior author Tae Kyun Kim, MD,...

ntra-articular corticosteroids are a good early treatment for knee osteoarthritis pain, according to a meta-analysis by Boston-based researchers. However, hyaluronic acid injected into the knee joint appears to be more effective in the long term. In the December 15th issue of Arthritis and Rheumatism, Dr. Timothy E. McAlindon of Tufts University...

- indications for HTO:
- associated conditions:
- posterolateral corner deficiency
- osteoarthritis of the knee:
- motivation for procedure:
...

Genetics highlights relationships between biological systems, and as the number of defi ned osteoarthritis susceptibility alleles increases, there is the natural tendency to assess whether the alleles infl uence other musculoskeletal phenotypes. That has proven to be the case for the GDF5 polymorphism rs143383, a risk factor for knee osteoarthritis and several other common conditions, including lumbar-disc degeneration...

Degenerative joint disease can affect any or all of the compartments of the knee joint. This article addresses arthrosis that is localized to the lateral compartment of the knee. The typical radiographic signs that are associated with degenerative joint disease consist of narrowing of the joint space, subchondral cyst formation, bone...

Using Viscosupplementation to Improve Patient Outcomes CME William Arnold, MD; Andrew I. Spitzer, MD
Treatment goals for these patients include a reduction in pain, an improvement in joint mobility, and to limit functional impairment. To properly manage OA, both nonpharmacologic and pharmacologic modalities may be employed. Intra-articular viscosupplementation with hyaluronate-derived products...

Optimal surgical management of the unicompartmental osteoarthritic knee has eluded the orthopedist for decades. McKeever is credited with recognizing that arthritis of the knee could be unicompartmental in nature. Treatment options for medial compartment arthritis have varied extensively, including valgus unloading braces; opening or closing wedge osteotomies of the proximal...

This x-ray demonstrates mild medial compartment osteoarthritis of the knee associated with anterior cruciate ligament deficiency. There is a significant varus alignment present in both knees.
Controversies in Sports Medicine

Questions/purposes We therefore asked whether laterally wedged insoles or valgus braces would reduce pain, enhance functional scores, and correct varus malalignment comparable to knee braces.
Conclusions Our data suggest a laterally wedged insole may be an alternative to valgus bracing for noninvasively treating symptoms of medial knee OA.
Medial knee osteoarthritis treated by insoles...

Osteoarthritis is a common, chronic condition which requires an individualised management plan involving multiple kinds of treatment.
Exercise programs and the Arthritis
Self-Management Program reduce pain and disability associated with osteoarthritis.
Paracetamol is the most appropriate first-line analgesic.
Non-steroidal anti-inflammatory drugs may be used as second-line analgesia on an as-needed basis (including continuous...

February 27, 2008 — The Osteoarthritis Research Society International (OARSI) has issued 25 evidence-based, expert consensus recommendations for the management of osteoarthritis (OA) of the hip and knee. These guidelines, which are published in the February issue of Osteoarthritis and Cartilage, were intended to be adapted for use in different...