Orthopedics > OCOSH Classification > Bone Diseases > Orthopaedic Oncology > Connective and Soft Tissue Neoplasms > Connective Tissue Neoplasms > Synovial Sarcoma > Page 2

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A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)

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Synovoal Sarcoma Wikipedia

Location: http://en.wikipedia.org/wiki/Synovial_sarcoma

Synovial sarcoma is a rare soft-tissue sarcoma defined by the presence of a unique translocation, t(X;18)(q11.2;p11.2). It usually occurs adjacent to joints in the limbs and was originally thought to arise from synovium. However, synovial sarcoma is a misnomer and the origin of the tissue is unknown. Primary synovial sarcomas have...
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