Orthopedics > OCOSH Classification > Bone Diseases > Orthopaedic Oncology > Connective and Soft Tissue Neoplasms > Connective Tissue Neoplasms > Synovial Sarcoma

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A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)

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adjuvant therapy for a resected synovial sarcoma

Location: http://www.medscape.com/viewarticle/413517

Question A 24-year-old female underwent excision of a 3-cm monophasic synovial sarcoma in the posterior low neck in Mexico. The tumor had 5 mitoses/10 hpf. The patient underwent another wide re-excision in the United States with no evidence of sarcoma in the specimen. The metastatic workup was negative. Does she need...
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Small Cell Variant of Synovial Sarcoma

Location: http://www3.interscience.wiley.com/cgi-bin/abstract/72509612/ABSTRACT?CRETRY=1&SRETRY=0

Diagnostic Dilemmas Small-cell variant of synovial sarcoma: Fine-needle aspiration with ancillary features and potential diagnostic pitfalls Jan F. Silverman, M.D. 1 *, Rodney J. Landreneau, M.D. 2, Charles D. Sturgis, M.D. 1, Stephen S. Raab, M.D. 1, Karl R. Fox, M.D. 1, Katherine M. Jasnosz, M.D. 1, David J. Dabbs, M.D....
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Synovial Cell Sarcoma eMedicine Orthopedics

Location: http://www.emedicine.com/orthoped/topic564.htm

Contents - Author Information; Introduction; Relevant Anatomy And Contraindications; Workup; Treatment; Complications; Outcome And Prognosis; Future And Controversies; Pictures; Bibliography
Synovial sarcoma is a rare soft tissue sarcoma with features of epithelial differentiation. In contrast with its name, synovial sarcoma is not associated with synovial joints. It tends to arise in...
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Synovial Sarcoma Atlas Genetics Cytogenetics

Location: http://atlasgeneticsoncology.org/Tumors/SynovSarcID5044.html

rare soft tissue tumor, it accounts for up to 5 to 8% of soft tissue sarcomas , the fourth most common type of sarcoma after malignant fibrous histyocytoma, liposarcoma and rhabdomyosarcoma ; the most common pediatric non rhabdomyosarcomatous soft tissue cancer; average incidence : 2,75 per 100000 population based on...
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synovial sarcoma CHORUS

Location: http://chorus.rad.mcw.edu/doc/00466.html

soft-tissue mass, usually about 1 cm from joint
*amorphous calcifications (33%)
*most common at knee
*bone erosion (wide zone of transition)
*juxta-articular osteoporosis
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Synovial Sarcoma Doctors Doctor

Location: http://www.thedoctorsdoctor.com/diseases/synovial_sarcoma.htm

This is one of the sarcomas that combine histologic features of both a carcinoma and a sarcoma. It may have epithelioid cells, mimicking carcinoma, intimately admixed with spindled sarcoma cells. Because of these features, the pathologist may have to differentiate between a poorly differentiated carcinoma and this tumor. It is...
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Synovial Sarcoma eMedicine Radiology

Location: http://www.emedicine.com/radio/topic668.htm

Contents Introduction Differentials Radiograph CT SCAN Mri Ultrasound Nuclear Medicine Angiography Intervention Multimedia References
Synovial sarcoma comprises 8-10% of all sarcomas and most commonly affects adults in the third-to-fifth decades of life. The malignancy most commonly involves the extremities, especially the lower extremities around the knees. Synovial sarcoma frequently is...
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Synovial Sarcoma Histopathology India

Location: http://www.histopathology-india.net/SS.htm

Synovial sarcoma is a well defined entity which commonly occurs in adolescents and young adults. (between 15 and 40 years of age).
This tumour is commonly located in the paraarticular regions, close to tendon sheaths, bursae and joint capsules. The tumour rarely involves synovial membrane.
Site: These are usually located ...
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Synovial Sarcoma mimicking Haemophilic Pseudotumour

Location: http://www.hindawi.com/GetArticle.aspx?doi=10.1155/SRCM/2006/27212

Sarcoma Volume 2006 (2006), Article ID 27212, 3 pages
Haroon A. Mann et al
This is a case of a 36-year-old gentleman with haemophilia A who was presented with an acute atraumatic soft tissue swelling in the right thigh. Open biopsy was performed with the resultant diagnosis of a synovial cell sarcoma....
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Synovial Sarcoma of the Shoulder Radiology Case

Location: http://www.kinderradiologie-online.de/radiology/20020124110219.shtml

History: For 2 weeks, a painless swelling in the left cervical area and in the suprapit. Surgical aspiration of the mass. Diagnosis: hematoma. After 6 months, severely increased swelling.
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Synovial Sarcoma Orthopaedia

Location: http://www.orthopaedia.com/display/Main/Synovial+sarcoma

Synovial sarcoma is a malignant soft tissue sarcoma that usually involves tendon sheaths, bursae, and the joint capsule; however, it rarely invades the joint itself. Joint cavity involvement has been reported to occur in 5-10% of patients. It is commonly found in close proximity to the large joints...
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Synovial Sarcoma Questions and Answers NCI

Location: http://www.cancer.gov/cancertopics/factsheet/Sites-Types/synovial

Key points Synovial sarcoma is a rare type of soft tissue sarcoma that occurs mostly in young adults (see Questions 1 and 2). The most common symptoms are swelling or a mass, occasionally accompanied by pain or tenderness (see Question 4). Surgery is the usual treatment for synovial sarcoma (see Question...
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Synovial Sarcoma RadPOD

Location: http://www.radpod.org/2007/06/09/synovial-sarcoma/

Radiology Picture of the Day June 2007.
This 35yr old patient presented with swelling on the back of his knee for 6 months. The swelling is not particularly tender and was initially discovered incidentally.
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