Orthopedics > OCOSH Classification > Bone Diseases > Orthopaedic Oncology > Connective and Soft Tissue Neoplasms > Connective Tissue Neoplasms > Fibrous Tissue Neoplasms > Histiocytoma > Malignant Fibrous Histiocytoma

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The most commonly diagnosed soft tissue sarcoma. It is a neoplasm with a fibrohistiocytic appearance found chiefly in later adult life, with peak incidence in the 7th decade.

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Early Sarcomatous Degeneration near a cementless hip replacement

Location: http://www.jbjs.org.uk/cgi/reprint/74-B/5/740

J Bone Joint Surg Br. 1992 Sep;74(5):740-4
Jacobs JJ, Rosenbaum DH, Hay RM, Gitelis S, Black J. Department of Orthopaedic Surgery, Rush-Presbyterian-St Luke's Medical Centre, Chicago, Illinois 60612. We present the case of a 65-year-old man who developed a malignant fibrous histiocytoma at the lesser trochanter five months after a cementless hip replacement....
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Fibrosarcoma of long bones. A study of the significance of areas of malignant fibrous histiocytoma.

Location: http://www.jbjs.org.uk/cgi/reprint/67-B/1/111

J Bone Joint Surg Br. 1985 Jan;67(1):111-6
Taconis WK, van Rijssel TG. A study was made of the clinical course of 102 cases of fibrosarcoma of long bones. Of these, 55 were predominantly fibroblastic or pure fibrosarcomata while 47 contained extensive areas resembling so-called malignant fibrous histiocytoma (MFH). Treatment was similar...
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Fibrosarcomata and malignant fibrous histiocytomata arising in relation to enchondromata

Location: http://www.jbjs.org.uk/cgi/reprint/61-B/3/366

J Bone Joint Surg Br. 1979 Aug;61-B(3):366-72
Fibrosarcomata and malignant fibrous histiocytomata arising in relation to enchondromata.Sanerkin NG, Woods CG. Six cases are reported in which a fibrosarcoma or malignant fibrous histiocytoma developed in relation to an enchondroma in a long bone. Four of the tumours were fibrosarcomata, and two were...
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Malignant fibrous histiocytoma

Location: http://www.jbjs.org.uk/cgi/reprint/61-B/2/190

J Bone Joint Surg Br. 1979 May;61-B(2):190-3
Malignant fibrous histiocytoma: an unusual lesion of interest to the orthopaedic surgeon.Spector DB, Miller J, Viloria J.
Malignant Fibrous Histiocytoma is an unusual musculoskeletal tomour which typically presents in the fifth and sixth decades. Extensive radiologic and laboratory investigations are seldom helpful in diagnosis,...
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Malignant Fibrous Histiocytoma Doctors Doctor

Location: http://www.thedoctorsdoctor.com/diseases/mfh.htm

This has become the most common malignant sarcoma of older adults. It tends to occur in the deep soft tissue of the extremities and the retroperitoneum. However, it has been described in nearly every organ of the body. Signs and symptoms relate directly to the location in which it arises....
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Malignant Fibrous Histiocytoma eMedicine Radiology

Location: http://www.emedicine.com/radio/topic420.htm

Background: Malignant fibrous histiocytoma (MFH), described by O'Brien and Stout in 1964, is the most common soft tissue sarcoma of late adult life. Pathophysiology: Uncertain histogenesis and numerous subtypes make MFH a rather controversial entity. Researchers have postulated both histiocytic and primitive mesenchymal cell theories of origin. In general, the tumor...
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Malignant fibrous histiocytoma of bone at the site of a total hip arthroplasty

Location: http://www.jbjs.org.uk/cgi/reprint/66-B/1/38

J Bone Joint Surg Br. 1984 Jan;66(1):38-40
Malignant fibrous histiocytoma of bone at the site of a total hip arthroplasty. A case report.Bagó-Granell J, Aguirre-Canyadell M, Nardi J, Tallada N. A patient who presented with a malignant fibrous histiocytoma in the proximal femur after a total hip replacement is reported. The...
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Malignant fibrous histiocytoma Orthopaedia

Location: http://www.orthopaedia.com/display/Main/Malignant+fibrous+histiocytoma+%28MFH%29

Malignant fibrous histiocytoma (MFH) is a tumor of mesenchymal origin that exhibits a heterogeneous histology of spindle cells in a characteristic storiform or "starry night" pattern. The most common soft tissue malignancy in adults, MFH comprises 1 to 5% of all primary bone tumors. The World Health Organization has recently...
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Malignant Fibrous Histiocytoma Pre-test and tutorial

Location: http://dev.slackinc.com/aaosdemo/Tutorials/tumors/malignant/default.cfm

Malignant Fibrous Histiocytoma Pre-test and tutorial Frank J. Frassica, MD Professor of Orthopaedics & Oncology Johns Hopkins University Department of Orthopaedic Surgery Baltimore, Maryland Franklin H. Sim, MD Chief, Section of Orthopedic Oncology Mayo Clinic Rochester, Minnesota Section of Orthopedics Hyperguide
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Malignant Fibrous Histiocytoma Wheeless

Location: http://www.wheelessonline.com/ortho/malignant_fibrous_histiocytoma

Osseous Sarcoma: - occur less often in bone than in soft tissue; - occurs in older patient population & may arise out of Pagets Dz or from a bone infarct (such as sickle cell); - it usually presents as an aggressive...
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Malignant soft-tissue tumour at the site of a total hip replacement

Location: http://www.jbjs.org.uk/cgi/reprint/66-B/5/629

J Bone Joint Surg Br. 1984 Nov;66(5):629-31
Swann M. A case is reported of a patient who presented with a soft-tissue tumour at the site of a total hip replacement. This tumour proved to be a malignant fibrous histiocytoma.
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Orthopaedic Literature Search for MFH

Location: http://pubmed.gov

Search String malignant fibrous histiocytoma (jrid22024 OR jrid2275 OR jrid2208 OR jrid32471 OR jrid3046 OR jrid1981 OR jrid22800 OR jrid22785 OR jrid3221 OR jrid6314 OR jrid20148 OR jrid3758 OR jrid32378 OR jrid32364 OR jrid147 OR jrid30151 OR jrid148 OR jrid149 OR jrid352 OR jrid20176 OR jrid445 OR jrid1588 OR jrid8735...
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Osteosarcoma - Malignant Histiocytoma of Bone

Location: http://www.meb.uni-bonn.de/cancer.gov/CDR0000062698.html

Contents - General Information Prognostic Factors Cellular Classification Staging and Site Information Treatment Option Overview Localized Osteosarcoma/Malignant Fibrous Histiocytoma of Bone Metastatic Disease at Diagnosis Recurrent Osteosarcoma
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