Plasmacytoma (Subscribe)  

From database of clinical trials recuiting patients

A plasmacytoma is a discrete, solitary mass of neoplastic monoclonal plasma cells in either bone or soft tissue (extramedullary). Types are as follows: Soft-tissue (extramedullary) plasmacytoma (SEP) Solitary bone plasmacytoma (SBP) Multifocal form of multiple myeloma Multiple myeloma Plasmablastic sarcoma To simplify, solitary plasmacytomas can be divided into 2 groups according to location:...

Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma. National Guideline Clearinghouse

Multiple Myeloma and Other Plasma Cell Neoplasms (PDQ®): Treatment
Multiple myeloma is a systemic malignancy of plasma cells that is highly treatable but rarely curable. It is potentially curable when it presents as a solitary plasmacytoma of bone or as an extramedullary plasmacytoma. The median survival in the prechemotherapy era was...

The Doctor's Doctor Plasmacytoma is a localized collection of monoclonal plasma cells. The disease is divided into primary plasmacytoma of the bone and extramedullary plasmacytoma. The importance of the diagnosis rests with the potential for these disorders to progress to multiple myeloma. Solitary plasmacytoma of the bone are usually painful and...

Radiology case 4411-3451 Clinical presentation: 60 year old man with left buttock pain, getting worse for the last 10 years. Monoclonal gammopathy, IGG.
There is a lytic expansion of the left ilium by a cyst like lesion with a multi-loculate appearance. The lesion extends from the left acetabulum through the ilium, but...

Radiology case 454-3451 Clinical presentation: 43 year old female with pain in leg after a fall.
Well circumscribed expanding lesion in the proximal metaphysis and adjacent diaphysis of the left tibia. Anteriorly in the lateral view, a stepped break in the cortex over the lesion indicates a fracture and is probably responsible...

Plasmacytoma amd multiple myeloma are both patterns of bone destruction, produced by an accumulation of plasma cells. The disease occurs in late middle age with a peak incidence at 60 years. Males are more likely to be affected, 2:1. The single mass of plasmacytoma is lytic and expands the bone...

Discussion of isolated bone plasmacytoma IBP
Emmanuel K. Konstantakos, MD; Lynn A. Crosby, MD, FACS eMedicine Case Presentations CME © 2009

Skeletal Plasmacytoma: Progression of disease and impact of local treatment; an analysis of SEER database Muhammad UMAR Jawad and Sean P Scully Journal of Hematology & Oncology 2009, 2:41 Full text available
Background Previous reports suggest an as yet unidentifiable subset of patients with plasmacytoma will progress to myeloma. The current study...

Abstract Less than 5% of patients with a plasma cell dyscrasia present with a single bone (SBP) or extramedullary plasmacytoma (EMP) without evidence of systemic disease (normocalcemia, absence of anemia, preservation of uninvolved immunoglobulins, or renal disease attributable to myeloma). Diagnosis requires biopsy confirmation of a monoclonal plasma cell infiltrate from...

solitary plasmacytoma