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Pagets disease disease of unknown etiology involving destruction and reparation

Contributor: Christopher J Bennett - National Capital Consortium Paget's disease at osseous scintigraphy Factoid 4755 - Created: 2003-04-24 12:50:56-04 - Modified: 2003-05-04 19:15:37-04 ACR Codes: 4.5 Paget’s disease is characterized by high rates of bone turnover and the formation of abnormal, weak bone. It is extremely common, found in...

Paget disease is a localized disorder of bone remodeling that typically begins with excessive bone resorption followed by an increase in bone formation. This osteoclastic activity followed by compensatory bone formation (osteoblastic activity) leads to a structurally disorganized mosaic of bone (woven bone), which is weaker mechanically, larger, less compact,...

Contributor: James H. Chang Paget Disease of Bone Factoid 3596 - Created: 2002-01-29 22:10:01-05 - Modified: 2002-04-17 09:18:33-04 ACR Codes: 4.7 Paget disease (osteitis deformans) is a condition of unknown cause affecting approximately 3 per cent of the population over age 40 years. Paget disease appears to be particularly...

Contributor: Sara Buckelew, medical student Paget Disease of Bone Factoid 1288 - Created: 2001-03-07 09:15:37-05 - Modified: 2001-03-14 17:01:08-05 ACR Codes: 4.84 Paget disease of bone involves localized, uncontrolled formation of highly active osteoclasts. Initial bone resorption is followed by an intense increase in osteoblastic activity. The bone that...

Paget disease is a metabolic bone disease characterized by excessive bone resorption and formation due to activated osteoclasts.

Paget disease of the bone (osteitis deformans) is a metabolic disorder characterized by abnormal osseous remodeling.

Paget disease, characterized by excessive and abnormal remodeling of bone, is a common disorder in middle-aged and elderly patients. The excessive remodeling gives rise to bones that are extensively vascularized, weak, enlarged, and deformed with subsequent complications.

Overview of this bone disorder including information on cause, facts and myths, symptoms, diagnosis, and treatment.

Paget's Disease of Bone Definition Incidence Aetiology Clinically Investigations Pathology Treatment Differential Diagnosis Complications Recent Literature

Clinical presentation: 80 year old lady with pain in her right hip. There is increased density of the right hemi-pelvis. The bone dimensions are increased. There is coarsening of the bone architecture with loss of detail. There is protrusio acetabulae, indicating bone softening. ACR-code 448-843

Radiology case 438-843: Pagets Disease

Radiology case 468-842: _Pagets Disease Tibia

Wheeless' Textbook of Orthopaedics Discussion: - a chronic progressive disease osteoblasts and osteoclasts which results in abnormal bone remodeling; - etiology, staging, and pathogenesis - prevalence: - uncommon...

Paget's Disease Topic 2602 - Created: 2001-07-27 05:09:01-04 - Modified: 2002-04-30 23:00:33-04 ACR Index: 4.2 -------------------------------------------------------------------------------- Paget’s disease most commonly occurs in England, Australia, New Zealand, Scandanavia, Canada and the northern U.S. The average age of onset is between 50 and 55 years. It is twice as common in men as...