Hyperparathyroidism (Subscribe)  

There is an expanding lesion of the upper metaphysis of the right humerus. It thins the cortex from below and appears multiloculate. There is a thin zone of transition between the lesion and normal bone.

Also known as: von Recklinhausen disease II von Recklinghausen’s disease of bone Associated persons: Gerhard Engel Friedrich Daniel von Recklinghausen Description: Now mostly historical term for a generalized rarefying bone disorder with skeletal deformation, seen in advanced hyperparathyroidism. It is characterized by cysts or brown tumours in the form of deeply pigmented foci consisting of fibrous scarring...

Wheeless' Textbook of Orthopaedics Discussion: - a disorder which is caused by excessive production of parathyroid hormone which leads to hypercalcemia, recurrent nephrolithiasis, pancreatitis, peptic ulcers, and mental changes; - incidence of approx...

	1'	2'
brown tumor	+++	++
chondrocalcinosis	+	rare
osteosclerosis	rare	+++
periostitis	rare	+

"WHAT: Hyperparathyroidism. Hyperparathyroidism: a condition due to an increase in the secretion of the parathyroids, causing generalized osteitis fibrosa cystica, elevated serum calcium, decreased serum phosphorus, and increased excretion of both calcium and phosphorus. WHY: Several rheumatological disorders are associated with hyperpara- thyroidism. First, hyperuricemia and gouty arthritis (which may...

Radiology case 438-5319 Clinical presentation: Spontaneous fracture of the neck of the right femur precipitated a hospital admission for this middle aged male, where a markedly raised serum calcium was identified. Eventually, a small mass was removed from the neck.
The images show acro-osteolysis of the terminal phalanges, which improved in...

a disorder which is caused by excessive production of parathyroid hormone which leads to hypercalcemia, recurrent nephrolithiasis, pancreatitis, peptic ulcers, and mental changes; - incidence of approx 5 /10,000 pts per year; ...

Objectives
1. Describe the effect of parathyroid hormone on skeletal metabolism
2. Describe symptoms which are compatible with hyperparathyroidism or hypoparathyroidism in children

"A condition of abnormally elevated output of PARATHYROID HORMONE due to parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. It is characterized by the combination of HYPERCALCEMIA, phosphaturia, elevated renal 1,25-DIHYDROXYVITAMIN D3 synthesis, and increased BONE RESORPTION."

Illustrated cases from the experience of Dr Vinod Naneria, Indore, MP, India
Cases include synovial chondromatosis, fibromatosis, haemangiomas, Osteochondritis dissecans, Multiple Myeloma, Osteoid Osteoma, Osteochondroma, Lipoma, Fibroma, Non-ossifying Fibroma, Fibrous cortical defects, Paget Disease, Osteogenesis Imperfecta, Osteopetrosis, Hyperparathyroidism, Neurofibromatosis, Neurilemoma

"Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY."

Hyperparathyroidism, tertiary may be caused by or feature of Miscellaneous syndromes Malabsorption syndrome Renal failure, chronic may cause or feature Biochemical abnormalities Alkaline phosphatase bone isoenzyme levels raised (plasma or serum) Hypercalcaemia Hyperparathyroidism Hypophosphataemia