Osteolysis (Subscribe)  

loss of terminal tufts of digits; found in
* scleroderma / connective-tissue disease
* psoriatic arthritis
* Reiter disease
* frostbite(thumbs spared)/burns
* leprosy
* polyvinylchloride exposure
* hyperparathyroidism
...

Distal clavicle osteolysis was first described in 1936 as a condition secondary to acute shoulder trauma. Today, distal clavicle osteolysis is described as a sequela of trauma associated with contact sports, falls, and motor vehicle accidents. In 1959, this condition was reported in an air-hammer operator without evidence of acute...

The most common skeletal manifestation of malignancy is focal osteolysis in association with metastases. In order for tumor cells to grow and invade mineralized bone, osteolysis must occur. Osteoclasts appear uniquely adapted to produce the microenvironment and the biochemical milieu that are needed to resorb bone. Although previous reports have...