Periprosthetic Osteolysis (Subscribe)  

Wheeless Textbook of Orthopaedics (THR) - Loosening of Uncemented Acetabular Components: (press fit acetabular components) - normal bone ingrowth: - generally for bone ingrowth to occur, the component must lie with 50 micrometers of the...

This process occurs when tiny particles are generated at the bearing couple of a joint replacement. Since most joint replacements use polyethylene (a type of plastic) as one of the bearing surfaces, and since this is usually the softer material, most of the tiny particles will be polyethylene. The ones... Expert

Chapter 24: Epidemiology of Osteolysis: Backside Implant Wear, ICL 53 Gerard A. Engh, MD; Deborah J. Ammeen, BS Engh GA, Ammeen DJ. Epidemiology of Osteolysis: Backside Implant Wear. Instr Course Lect 2004;53:243-249. ABSTRACT: Osteolysis is an emerging problem in patients who undergo total hip arthroplasty and total knee arthroplasty (TKA). Before the...

OTA poster/paper 1998 The etiology of the radiographic findings of osteolysis and periosteal reaction is not specifically known, but the presence of corrosion products at the taper junctions suggests particulate debris as a factor. There was an association between the radiographic abnormalities (osteolysis and periosteal reaction) and thigh pain and elevated...

Report on AAOS 2000
Spiral CT for Diagnosing Acetabular Osteolysis After THA
Reoperation of Failed Cementless Sockets for Polyethylene Wear and Pelvic Osteolysis
Femoral Osteolysis after THA
Diagnosis and Treatment of Pelvic Discontinuity in Revision Hip Arthroplasty

Radiology site.Very well illustrated
# AKA particle disease, aggressive granulomatosis
# Particulate debris from wear of arthroplasty components, most commonly polyethylene component

The effects of osteolysis and aseptic loosening were highlighted at an orthopaedic Grand Rounds presentation at the University of Pittsburgh on October 20, 2000, hosted and led by Dr. Raj Sinha, with a presentation by Dr. Marshal Peris.
Medscape Orthopaedics & Sports Medicine eJournal 5(1), 2001.

Wheeless Textbook of Orthopaedics Discussion: - most common complication in total hip arthroplasty and most common cause of component failure; - osteolysis is a time dependent process which arises from inflammatory reaction against polyethylene particulate debris; - patho-biology: ...