Periprosthetic Osteolysis (Subscribe)  

The treatment of asymptomatic osteolysis among well-fixed cementless cups remains controversial. To compare the effectiveness of different treatment strategies, an objective technique for evaluating bone remodeling would be useful. By matching and comparing serial CT images with the aid of a computer-assisted imaging program, we developed a method to evaluate...

Wheeless Textbook of Orthopaedics (THR) - Loosening of Uncemented Acetabular Components: (press fit acetabular components) - normal bone ingrowth: - generally for bone ingrowth to occur, the component must lie with 50 micrometers of the...

This process occurs when tiny particles are generated at the bearing couple of a joint replacement. Since most joint replacements use polyethylene (a type of plastic) as one of the bearing surfaces, and since this is usually the softer material, most of the tiny particles will be polyethylene. The ones... Expert

Healing of acetabular bone grafts may be difficult to assess in conventional radiographs. We used PET to analyze healing of morselized bone allografts, impacted in large osteolytic acetabular defects at revision arthroplasty.
NTERPRETATION: We found PET to be a sensitive and useful method for evaluation of the spatial and temporal development...

Questions/purposes We therefore asked (1) whether macrophages associated with polyethylene particle-induced chronic inflammation are recruited locally or systemically and (2) whether the recruited macrophages are associated with enhanced osteolysis locally.
Conclusions Infusion of clinically relevant polyethylene particles, similar to the human scenario, stimulated systemic migration of remotely injected macrophages...

OTA poster/paper 1998 The etiology of the radiographic findings of osteolysis and periosteal reaction is not specifically known, but the presence of corrosion products at the taper junctions suggests particulate debris as a factor. There was an association between the radiographic abnormalities (osteolysis and periosteal reaction) and thigh pain and elevated...

Topics in the Reconstructive Orthopaedics section displayed in the left hand panel. Mostly Hip and Knee arthroplasty. Initial topic Wear and Osteolysis

Report on AAOS 2000
Spiral CT for Diagnosing Acetabular Osteolysis After THA
Reoperation of Failed Cementless Sockets for Polyethylene Wear and Pelvic Osteolysis
Femoral Osteolysis after THA
Diagnosis and Treatment of Pelvic Discontinuity in Revision Hip Arthroplasty

Radiology site.Very well illustrated
# AKA particle disease, aggressive granulomatosis
# Particulate debris from wear of arthroplasty components, most commonly polyethylene component

The effects of osteolysis and aseptic loosening were highlighted at an orthopaedic Grand Rounds presentation at the University of Pittsburgh on October 20, 2000, hosted and led by Dr. Raj Sinha, with a presentation by Dr. Marshal Peris.
Medscape Orthopaedics & Sports Medicine eJournal 5(1), 2001.

Wheeless Textbook of Orthopaedics Discussion: - most common complication in total hip arthroplasty and most common cause of component failure; - osteolysis is a time dependent process which arises from inflammatory reaction against polyethylene particulate debris; - patho-biology: ...