Osteogenesis Imperfecta (Subscribe)  

Podium No: 331 Thursday, February 15, 2007 04:00 PM - 04:06 PM Location: San Diego Convention Center Room 6DE
Mininder S Kocher, MD, MPH Boston MA (n) Laura Dichtel, AB Boston MA (n) Ingrid Holm, MD, MPH (n) Moderator(s): Lori A Karol, MD Dallas TX (N) Susan A Scherl, MD...

Podium No: 280 Thursday, February 15, 2007 02:42 PM - 02:48 PM Location: San Diego Convention Center Room 6DE
James J McCarthy, MD Philadelphia PA (b-EBI) John P Dormans, MD Philadelphia PA (b-Medtronic) Ross Chafez, MPH, DPT (n) Jared Friedman, BA (n) Timothy Roberts, BA (n) Brian Newton, BS (n)...

Early cyclical neridronate treatment has positive effects on growth and fracture rate in infants with severe osteogenesis imperfecta (OI), according to researchers. In a study published in the August issue of the Journal of Pediatrics, Italian researchers prospectively assessed the efficacy of bisphosphonate treatment in infants with severe OI. Included in...

Search String "osteogenesis imperfecta" orthopaedic OR orthopedic

Osteogenesis Imperfecta (OI) is a group of inherited disorders in which the most common feature is bones that break easily. OI results from an alteration either in the chemical makeup or production of collagen. Collagen is the protein "glue" that holds the body's tissues together and gives strength to bones. It... Expert

Osteogenesis Imperfecta Congenita OIC Alternative titles; OSTEOGENESIS IMPERFECTA CONGENITA, NEONATAL LETHAL FORM OSTEOGENESIS IMPERFECTA, TYPE II OI, TYPE II VROLIK TYPE OF OSTEOGENESIS IMPERFECTA

Osteogenesis Imperfecta: "Autosomal dominant COLLAGEN DISEASES resulting from defective biosynthesis of COLLAGEN TYPE I and characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. There are four major types, I-IV." Source: Medical Subject Headings, 2007_2006_08_08 "autosomal dominant collagen disease resulting from...

Osteogenesis imperfecta (OI) is disorder with congenital bone fragility, caused by mutations in the genes that codify for type I

Background: The earliest known case of osteogenesis imperfecta is in a partially mummified infant's skeleton from ancient Egypt now housed in the British Museum in London. In 1835, Lobstein coined the term osteogenesis imperfecta and was one of the first to correctly understand the etiology of the condition. Other names...

Background: Osteogenesis imperfecta (OI) is a common heritable disorder of collagen synthesis that results in weak bones that are easily fractured and often deformed. Several distinct subtypes have been identified. All of them lead to variable degrees of micromelic (short-limbed) dwarfism. Depending on severity, the bone fragility may lead to...

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Summary Disease characteristics. Osteogenesis imperfecta (OI) is a group of disorders characterized by fractures with minimal or absent trauma, dentinogenesis imperfecta (DI), and, in adult years, hearing loss. The clinical features of OI represent a continuum ranging from perinatal lethality to individuals with severe skeletal deformities, mobility impairments, and very...

osteogenesis imperfecta (OI) is an inherited disorder of connective tissue (specifically, faulty collagen formation). Gene probes have elucidated mutations in genes that regulate collagen formation, resulting in defective conversion of reticulum fibers to adult collagen fibers. There are four clinical criteria — blue sclerae, fragile bones, otosclerosis, and poor dentition...

osteogenesis imperfecta is an inherited (autosomal dominant) disorder of collagen formation. Its incidence is about 1 in 30,000 with about 20,000 to 50,000 estimated cases in the United States. It is characterized by loss of bone density, bowing and fractures of bones. Abnormal maturation of the collagen molecule results in...

Synonyms of Osteogenesis Imperfecta Brittle Bone Disease Ekman-Lobstein Disease Lobstein Disease (Type I) OI Vrolik Disease (Type II) Disorder Subdivisions Osteogenesis Imperfecta Type I Osteogenesis Imperfecta Type II Osteogenesis Imperfecta Type III Osteogenesis Imperfecta Type IV General Discussion Osteogenesis imperfecta (OI) is a group of rare disorders affecting the connective tissue and characterized...