Acquired Hyperostosis Syndrome (Subscribe)  

Our patient's presentation is consistent with the syndrome known as SAPHO (synovitis, acne, pustulosis, hyperostosis and osteomyelitis), and formerly termed acne arthritis. The syndrome is characterized by severe scarring acne and related conditions; hyperostotic bone lesions (particularly in the clavicles and sternum); sacroiliitis; spondylitis; and, peripheral inflammatory arthritis.

This search was more productive than a search for Acquired Hyperostosis Syndrome but did find a lot of dermatological material

Search String "Acquired Hyperostosis Syndrome"[MAJR] URL http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&term=%22Acquired+Hyperostosis+Syndrome%22%5BMAJR%5D 111 articles Nov 2006

SAPHO Syndrome At A Glance SAPHO syndrome is a chronic disorder that involves the skin, bone, and joints. SAPHO is an eponym for the combination of synovitis, acne, pustulosis, hyperostosis, and osteitis. Some researchers feel that the SAPHO syndrome is related to the group of arthritis conditions which typically affect the...

Review by Prof. Fritz Schilling Definition - SAPHO syndrome is a disease combining osseaous and articular manifestations associated with skin manifestations. Three diagnostic criteria characterize SAPHO sydrome: 1. multifocal osteitis with or without skin manifestations 2. Sterile acute or chronic joint inflammation associateted with either pustules or psoriasis of thepalms and soles, or...

Abstract A middle aged man presented with a 4 year history of painful swelling of both knees and pustular acne on his back. The MRI scan of the knees showed gross synovitis, so did the histopathology of the synovium. A diagnosis of SAPHO syndrome was made and he was...

Definition Synovitis Acne -- commonly involving the face and upper back. Pustulosis -- usually involving the palms of the hands and/or soles of the feet (palmo-plantar pustulosis). Hyperostosis Osteitis SAPHO syndrome is thought to comprise a spectrum of disorders that share some clinical, radiologic and pathologic characteristics. An entity known as...

SAPHO syndrome is thought to comprise a spectrum of disorders that share some clinical, radiologic and pathologic characteristics. An entity known as chronic recurrent multifocal osteomyelitis (CRMO) was first described in 1972. Subsequently in 1978 several cases of CRMO were associated with clinical findings of palmoplantar pustulosis. Since then, a... Uncertain

A gentleman comes in complaining of right knee pain. He is a 48-year-old African American man who was transferred from the Infectious Disease Clinic to the Thayer Medical Service for possible septic arthritis. His symptoms essentially limited his right knee motion; he is not able to flex more than 30...