Successful therapy with low-dose colchicine in intermittent hydrarthrosis

Description: Intermittent hydrarthrosis (IH) is a very uncommon condition characterized by episodic attacks of synovitis, usually in the large joints and most commonly the knees. The features which distinguish it from other periodic syndromes, such as palindromic rheumatism, are the predictable periodicity of the attacks, with one or two episodes per month, and the normality of laboratory tests during the attacks. No successful treatment for preventing or aborting the attacks has been documented. Here we report two cases of IH which responded favourably to low doses of colchicine.
Successful therapy with low-dose colchicine in intermittent hydrarthrosis. Queiro-Silva R, Tinturé-Eguren T, López-Lagunas I. Rheumatology (Oxford). 2003 Feb;42(2):391-2. Full text