Metastatic bone lesions pathological fractures Orthopaedia

Description: More than one million new cases of cancer are diagnosed annually in the United States. The most common primary malignancies that metastasize to the bone are breast, lung, kidney, prostate, and thyroid carcinomas, which account for approximately 700,000 (www.seer.cancer.gov) new cases of cancer annually. Bone pain is often a significant problem in bone metastases, and pathologic fracture can severely restrict the patient's activities and quality of life and lead to complications resulting in death.