Previous | Next
2008 Osteoporosis and Spinal Cord Injury eMedicine PMR
One of the inevitable complications of spinal cord injury (SCI) is the associated osteoporosis that occurs predominantly in the pelvis and the lower extremities. The acute treatment of patients with SCI has always focused on the injury itself and on the immediate complications that subsequently arise. Bone loss as a consequence of SCI has been of secondary concern historically. Osteoporosis in persons with SCI was first studied in relation to calcium metabolism and the associated hypercalcemia and renal calculi that followed.
The differences between SCI-induced osteoporosis and other causes of bone loss (disuse), such as prolonged bed rest, space travel, and lower motor neuron disorders, have since become clearer. New technologies allow monitoring of osteoblastic and osteoclastic activity at the microscopic level, while modern radiographic techniques have allowed more refined studies to be undertaken at the macroscopic level.
Synonyms and related keywords: spinal cord injury, osteoporosis, osteoporosis and SCI, SCI-induced osteoporosis, functional electrical stimulation, FES, dual-energy radiographic absorptiometry scan, dual-energy X-ray absorptiometry scan, DRA, DXA
Author David Weiss, MD 2008
Type: Reference Material
Author/Contact: David Weiss, MD
Submitted by: admin
Added: Sun Aug 10 2008
Last Modified: Mon May 09 2011