Low-Grade Central Osteosarcoma eMedicine Orthopedics

Description: Osteosarcoma of bone is a high-grade tumor with a long-term survival rate of 60-85%. Several variants of osteosarcoma exist. High-grade variants include telangiectatic osteosarcoma, small-cell osteosarcoma, high-grade surface osteosarcoma, and secondary osteosarcoma. Other variants, such as low-grade central osteosarcoma, parosteal osteosarcoma, and periosteal osteosarcoma, are less aggressive entities with a lower rate of metastasis and a long-term survival rate approaching 90%. Low-grade central osteosarcoma is a rare variant of osteosarcoma that is often mistaken for fibrous dysplasia.
Synonyms and related keywords: well-differentiated intramedullary osteosarcoma, low-grade intraosseous osteosarcoma, central osteosarcoma of low-grade malignancy, low-grade endosteal osteosarcoma
Dedmond & Eady 2007