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Telangiectatic Osteosarcoma eMedicine Orthopedics

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Location: http://www.emedicine.com/orthoped/TOPIC566.HTM

Description: Osteosarcoma is the most common primary malignant bone tumor in children and adolescents. When first recognized, telangiectatic osteosarcoma was proposed to be a distinct clinical and pathologic entity.1 On the basis of subsequent findings that provided a better understanding of the condition's presentation and prognostic implications, telangiectatic osteosarcoma should be considered a variant of osteosarcoma. Telangiectatic osteosarcoma appears as a painful, radiographically lytic mass lesion in the metaphyseal portion of the long bones. It is characterized by dilated, blood-filled vascular spaces lined by malignant osteoblasts. These osteoblasts are separated by fibrous septa, which contain the malignant cells, multinucleated giant cells, and tumor osteoid.
Synonyms and related keywords: primary malignant bone tumor, osteosarcoma variant, lytic mass lesion in long bone metaphysis
Jhala et al 2008

Type: Reference Material
Author/Contact: Jhala et al
Institution: eMedicine
Primary Subject/Category:

Language: English

Submitted by: admin
Hits: 242
Added: Sun Mar 30 2008