Gorhams Disease or Massive Osteolysis

Description: Gorham’s disease is a rare disorder characterized by proliferation of vascular channels that results in destruction and resorption of osseous matrix. Since the initial description of the disease by Gorham and colleagues (1954) and by Gorham and Stout (1955), fifty years have elapsed but still the precise etiology of Gorham’s disease remains poorly understood and largely unknown. There is no evidence of a malignant, neuropathic, or infectious component involved in the causation of this disorder. The mechanism of bone resorption is unclear.
Full Text. Gorham’s Disease or Massive Osteolysis Dipak V. Patel, MD Clinical Medicine & Research Volume 3, Number 2 : 65 -74 2005